PrepTest 141, Section 3, Question 3
An organism is considered to have an infection(446 more words not shown)
If the hypothesis that CJD(30 more words not shown)
- AHas the patient(8 more words not shown)
- BDoes the patient(5 more words not shown)
- CHas the patient(19 more words not shown)
- DHas any member(10 more words not shown)
- EDoes the patient's(10 more words not shown)
Reading the passage
If prions cause CJD through the process described, look for evidence of that process in the patient. The useful prediction is abnormal prions or the plaque they produce in brain tissue. That would connect the diagnosis to the proposed mechanism.
Working the answers
- A
The text never connects a blow to the skull with abnormal prions or CJD. Head injury can sound relevant to a brain problem, but that link is missing here.
- B
Chronic insomnia is listed as a symptom. Occasional bouts are a weaker and different description, and the text doesn't make occasional sleeplessness a strong indicator of CJD. E instead looks for the physical result of the proposed disease process.
- C
Radiation causing genetic damage isn't connected to CJD in this account. That adds a mechanism the text doesn't supply.
- D
We aren't told CJD is inherited. A relative's history of any brain disease therefore doesn't establish the connection this diagnostic question needs.
- ECorrect
The abnormal prion cascade produces plaque consisting of thread-like structures, which accumulates in the brain and destroys nerve cells. Finding such abnormal structures in brain tissue would provide evidence of the very process proposed to cause CJD. This is a closer match than an occasional symptom or an unsupported risk factor.
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